Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in psoriasis in southern Turkey

Izmirli M., Sen B. B., Rifaioglu E., GÖGEBAKAN B., ALDEMİR Ö., Sen T., ...Daha Fazla

ANAIS BRASILEIROS DE DERMATOLOGIA, cilt.91, sa.5, ss.611-613, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 91 Sayı: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1590/abd1806-4841.20164766
  • Dergi Adı: ANAIS BRASILEIROS DE DERMATOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.611-613
  • Çukurova Üniversitesi Adresli: Hayır

Özet

Background: Psoriasis is a multigenic and multifactorial dermatological disease linked to cardiovascular diseases. Increased levels of homocysteine in patients with psoriasis have been demonstrated in many studies. The most frequently investigated genetic defect that plays a role in homocysteine metabolism is single point substitution (C to T) located on the 677th nucleotide of the methylenetetrahydrofolate reductase gene (MTHFR).