Vasculitis and leukemia

Paydas S., Zorludemir S., Sahin B.

LEUKEMIA & LYMPHOMA, cilt.40, ss.105-113, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40
  • Basım Tarihi: 2000
  • Doi Numarası: 10.3109/10428190009054886
  • Dergi Adı: LEUKEMIA & LYMPHOMA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.105-113
  • Anahtar Kelimeler: vasculitis, leukemia, CUTANEOUS NECROTIZING VASCULITIS, MYELODYSPLASTIC SYNDROMES, PARANEOPLASTIC-SYNDROME, MULTIPLE-SCLEROSIS, LEG ULCERS, PATIENT, HYDROXYUREA, INJECTIONS
  • Çukurova Üniversitesi Adresli: Evet

Özet

Vasculitis may accompany neoplasias and be of paraneoplastic type or associated with drugs used in patient treatment. We evaluated skin biopsies of twenty-eight cases with vasculitis accompanying leukemias reviewed and clinical outcome was evaluated. Eleven of the 28 cases had paraneoplastic vasculitis and 17 had vasculitis associated with various drugs including chemotherapy, cytokines and antibacterial agents. Paraneoplastic vasculitis was seen in 3 cases with chronic myelocytic leukemia in blastic phase, 5 patients with acute myeloblastic leukemia, and 3 with myelodysplastic syndrome. Drugs responsible for the 17 cases of vasculitis included hydroxyurea, vincristine, cytosine-arabinoside, methotrexate, all-trans retinoic acid, granulocyte-colony stimulating factor, interferon and antibiotics.