Prognostic importance of survivin, Ki-67, and topoisomerase II alpha in ovarian carcinoma

Gulec U. K., GÜMÜRDÜLÜ D., GÜZEL A. B., PAYDAŞ S., SEYDAOĞLU G., AÇIKALIN A., ...Daha Fazla

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.289, sa.2, ss.393-398, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 289 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s00404-013-3000-z
  • Dergi Adı: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.393-398
  • Anahtar Kelimeler: Epithelial ovarian cancer, Ki-67, Prognosis, Platinum resistance, Survivin, Topoisomerase II alpha, EXPRESSION, CANCER, APOPTOSIS, GENE, CHEMOTHERAPY, NUCLEAR, CELLS
  • Çukurova Üniversitesi Adresli: Evet

Özet

Stage, tumor grade and histological subtype determine the clinical behavior in ovarian tumors. Some additional factors are related to tumor cell biology and are the useful predictors for identifying the patients with poor prognosis. The aim of this study is to evaluate the prognostic significance of survivin, Ki-67 and Topoisomerase II alpha (TOPO II alpha) in epithelial ovarian cancer (EOC).